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ElDorado is
the Genomatix genome annotation. It is based on the publicly available reference
genome assemblies of 18
different organisms. Information from
a variety of different sources together with data generated by Genomatix' proprietary
algorithms is used to set up a database of more than 500 gigabytes of quality
checked data. The individual elements are highly linked to external data sources
(e.g. NCBI, Ensembl, TIGR, ...).
Representing a common sequence basis it allows us to integrate literature
based information about gene-gene interactions and pathway annotation from BiblioSphere
PathwayEdition
together
with experimental gene expression data e.g. from ChipInspector.
ElDorado Contents
- Transcripts with exon/intron structure, UTRs, CDS, and protein sequence
- Promoters for each transcript analysed for transcription factor
binding sites and regulatory modules
- CAGE tags, providing additional experimental support for full length transcripts
- PromoterInspector predictions
- microRNAs
- SNPs and their effects on transcription factor binding sites and protein
sequences
- genomic repeats
- SMARs
- genomic location for individual probes from Affymetrix chips
ElDorado Features
- The gene name query of ElDorado supports extended
lists of gene name synonyms and variants.
- Very fast algorithm for exon mapping evaluating
the cDNA for canonical splice sites
- Detailed gene information, integrating information
from different public sources (e.g. EntrezGene,
GeneOntology) with manually
curated gene-gene interactions by Genomatix.
- Comparative
Genomics (patent pending) allows you
to compare the annotation available for a group of
orthologous genes and to identify corresponding promoter
regions for the analysis of phylogenetically conserved
promoter elements.
- Literature analysis gives you access
to the genes cocited in the scientific literature
providing direct links to BiblioSphere
PathwayEdition
for
further in-depth analysis.
ElDorado Output
For each gene of interest, ElDorado lists information
based on the gene sequence and information based
on literature analysis.
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