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Publications & Patents

This is a selection of our own papers as well as several publications from our customers. You can learn how to apply our tools, read about successful collaborative research efforts, get a general overview from one of our reviews or dig into the details of our algorithms. There is also a list of patents where our methods or publications have been cited or our tools have been used for the application.

Collaborative research Genomatix Applications Customer applications Review articles Algorithms Patents  
 

Selected publications from our customers

(from a total of more than 4,000)

BiblioSphere

  • Heishi M, Hayashi K, Ichihara J, Ishikawa H, Kawamura T, Kanaoka M, Taiji M, Kimura T (2008)
    Comparison of gene expression changes induced by biguanides in db/db mice liver.
    J Toxicol Sci. 33,339-47
    [PUBMED: 18670165]
  • Sun C, Dobi A, Mohamed A, Li H, Thangapazham RL, Furusato B, Shaheduzzaman S, Tan SH, Vaidyanathan G, Whitman E, Hawksworth DJ, Chen Y, Nau M, Patel V, Vahey M, Gutkind JS, Sreenath T, Petrovics G, Sesterhenn IA, McLeod DG, Srivastava S (2008)
    TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation.
    Oncogene, June 9 [Epub ahead of print]
    [PUBMED: 18542058]
  • Vock C, Gleissner M, Klapper M, Döring F (2007)
    Identification of palmitate-regulated genes in HepG2 cells by applying microarray analysis.
    Biochim Biophys Acta. 1770, 1283-8
    [PUBMED: 17658692]
  • Platts AE, Dix DJ, Chemes HE, Thompson KE, Goodrich R, Rockett JC, Rawe VY, Quintana S, Diamond MP, Strader LF, Krawetz SA (2007)
    Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs.
    Hum Mol Genet. 16, 763-73
    [PUBMED: 17327269]
  • Deng X, Stachlewitz RF, Liguori MJ, Blomme EA, Waring JF, Luyendyk JP, Maddox JF, Ganey PE, Roth RA (2006)
    Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation.
    J Pharmacol Exp Ther. 319, 1191-9
    [PUBMED: 16990511]
  • Zindy PJ, L'Helgoualc'h A, Bonnier D, Le Bechec A, Bourd-Boitin K, Zhang CX, Musso O, Glaise D, Berangere Troadec M, Loreal O, Turlin B, Leger J, Clement B, Theret N (2006)
    Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis.
    Hepatology 44, 1296-307
    [PUBMED: 17058241]
  • Klein C, Bauersachs S, Ulbrich SE, Einspanier R, Meyer HH, Schmidt SE, Reichenbach HD, Vermehren M, Sinowatz F, Blum H, Wolf E (2006)
    Monozygotic twin model reveals novel embryo-induced transcriptome changes of bovine endometrium in the preattachment period.
    Biol Reprod 74, 253-64
    [PUBMED: 16207835]
  • Krones-Herzig A, Mittal S, Yule K, Liang H, English C, Urcis R, Soni T, Adamson ED, Mercola D (2005)
    Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.
    Cancer Res. 65, 5133-43
    [PUBMED: 15958557]
  • McLaughlin JN, Mazzoni MR, Cleator JH, Earls L, Perdigoto AL, Brooks JD, Muldowney JA 3rd, Vaughan DE, Hamm HE (2005)
    Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells.
    J Biol Chem. 280, 22172-80
    [PUBMED: 15817447]
  • Buckingham, S. (2003)
    Programmed for success (technology feature)
    Nature 425, 209-15

RegionMiner

ElDorado

  • Weickert CS, Miranda-Angulo AL, Wong J, Perlman WR, Ward SE, Radhakrishna V, Straub RE, Weinberger DR, Kleinman JE (2008)
    Variants in the estrogen receptor alpha gene and its mRNA contribute to risk for schizophrenia.
    Hum Mol Genet. 17, 2293-309
    [PUBMED: 18424448]

MatInspector

  • Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S (2008)
    REST maintains self-renewal and pluripotency of embryonic stem cells.
    Nature 453, 223-7
    [PUBMED: 18362916]
  • Ohnesorg T, Keller B, Hrabe de Angelis M, Adamski J (2006)
    Transcriptional regulation of human and murine 17beta-hydroxysteroid dehydrogenase type-7 confers its participation in cholesterol biosynthesis.
    J Mol Endocrinol. 37, 185-97
    [PUBMED: 16901934]
  • Ufer C, Borchert A, Kuhn H (2003)
    Functional characterization of cis- and trans-regulatory elements involved in expression of phospholipid hydroperoxide glutathione peroxidase.
    Nucleic Acids Res. 31, 4293-303
    [PUBMED: 12888488]
  • Liedtke C, Groger N, Manns MP, Trautwein C (2003)
    The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism.
    J Biol Chem. 278, 27593-604
    [PUBMED: 12748179]
  • Alpy F, Boulay A, Moog-Lutz C, Andarawewa KL, Degot S, Stoll I, Rio MC, Tomasetto C (2003)
    Metastatic lymph node 64 (MLN64), a gene overexpressed in breast cancers, is regulated by Sp/KLF transcription factors.
    Oncogene 22, 3770-80
    [PUBMED: 12802284]

GEMS Launcher

  • van Waveren C, Moraes CT (2008)
    Transcriptional co-expression and co-regulation of genes coding for components of the oxidative phosphorylation system.
    BMC Genomics 9, 18
    [PUBMED: 18194548]
  • Tarasov KV, Testa G, Tarasova YS, Kania G, Riordon DR, Volkova M, Anisimov SV, Wobus AM, Boheler KR (2008)
    Linkage of Pluripotent Stem Cell- Associated Transcripts to Regulatory Gene Networks.
    Cells Tissues Organs 188, 31-45
    [PUBMED: 18303244]
  • Yan B, Yang X, Lee TL, Friedman J, Tang J, Van Waes C, Chen Z (2007)
    Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-kappaB and other signal transcription factors in head and neck squamous cell carcinoma.
    Genome Biol. 8, R78
    [PUBMED: 17498291]
  • Uddin RK, Singh SM (2007)
    Ethanol-responsive genes: identification of transcription factors and their role in metabolomics.
    Pharmacogenomics J. 7, 38-47
    [PUBMED: 16652119]
  • Moss AC, Doran PP, MacMathuna P (2007)
    In Silico Promoter Analysis can Predict Genes of Functional Relevance in Cell Proliferation: Validation in a Colon Cancer Model
    Translational Oncogenomics 2007
    [http://www.la-press.com/journals.php?pa=toc&journal_id=19]
  • Lee TL, Alba D, Baxendale V, Rennert OM, Chan WY (2006)
    Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes.
    Genomics 88, 18-33
    [PUBMED: 16678385]
  • Smith JL, Freebern WJ, Collins I, De Siervi A, Montano I, Haggerty CM, McNutt MC, Butscher WG, Dzekunova I, Petersen DW, Kawasaki E, Merchant JL, Gardner K (2004)
    Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment.
    Proc Natl Acad Sci U S A. 101, 11554-9
    [PUBMED: 15286281]

ChipInspector

  • Fang J, Menon M, Kapelle W, Bogacheva O, Bogachev O, Houde E, Browne S, Sathyanarayana P, Wojchowski DM (2007)
    EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts.
    Blood 110, 2361-70
    [PUBMED: 17548578]
  • Sathyanarayana P, Menon MP, Bogacheva O, Bogachev O, Niss K, Kapelle WS, Houde E, Fang J, Wojchowski DM (2007)
    Erythropoietin modulation of podocalyxin and a proposed erythroblast niche.
    Blood 110, 509-18
    [PUBMED: 17403918]
  • Gehrig A, Langmann T, Horling F, Janssen A, Bonin M, Walter M, Poths S, Weber BH (2007)
    Genome-wide expression profiling of the retinoschisin-deficient retina in early postnatal mouse development.
    Invest Ophthalmol Vis Sci. 42, 891-900
    [PUBMED: 17251492]
  • Ecker J, Langmann T, Moehle C, Schmitz G (2007)
    Isomer specific effects of Conjugated Linoleic Acid on macrophage ABCG1 transcription by a SREBP-1c dependent mechanism.
    Biochem Biophys Res Commun. 352, 805-11
    [PUBMED: 17141191]
  • Loewe R, Valero T, Kremling S, Pratscher B, Kunstfeld R, Pehamberger H, Petzelbauer P (2006)
    Dimethylfumarate impairs melanoma growth and metastasis.
    Cancer Res. 66, 11888-96
    [PUBMED: 17178886]

SMARTest

  • Shaposhnikov SA, Akopov SB, Chernov IP, Thomsen PD, Joergensen C, Collins AR, Frengen E, Nikolaev LG (2007)
    A map of nuclear matrix attachment regions within the breast cancer loss-of-heterozygosity region on human chromosome 16q22.1.
    Genomics 89, 354-61
    [PUBMED: 17188460]