Projects

BFAM

Genomatix was a participant of the (now completed) project "Bioinformatics for Functional Analysis of Mammalian genomes" (BFAM) which was funded by the BMBF (German Federal Ministry for Education and Research) for a five years period and is part of the German National Genome Research Network (NGFN).

The goal within BFAM was to create hypotheses for higher organizational levels of promoters by comparative promoter analysis, to validate these results on base of experimental results in cooperation with our BFAM partners and to reconstruct parts of regulatory networks.

ChIP on Chips

Genomatix participated in the (now completed) "ChIP on Chips" (Development of Chromatin-immuno-precipitation on microarrays in mammals.) project funded by the BMBF (German Federal Ministry for Education and Research). This project was part of the German Proteomics Network.

Its aim was to develop technologies for the characterization of the regulatory proteome via chromatin-immuno-precipitation on chips. This should extend the prognostic potential of standard DNA microarrays by monitoring the state of genes independent of their expression. Long-term applications range from specific diagnostics, target identification and vector development in gene therapy.

BioChance

Genomatix has won a "BioChance" research contract from the BMBF (German Federal Ministry for Education and Research) to research RNAi mediated regulatory networks and to expand its competence and product line into this new field. The project is scheduled to run for two years and is worth more than US$ 1.6 million.

The aim of the project is genome wide annotation of RNAi and RNAi mediated regulatory networks. RNAi annotation will be integrated in ElDorado while the RNAi mediated networks will become an essential part of BiblioSphere PathwayEdition.

The experimental (wet lab) part of the project will be carried out by two academic research partners: the Ludwig-Maximilians-University Munich and the DKFZ Heidelberg.